By S. Eva Singletary, Geoffrey L. Robb
Edited through awesome leaders within the box of breast disorder (Dr. Singletary chairs the Breast melanoma Committee for the yankee collage of Surgeons), this publication deals first-hand recommendation on prevention, prognosis, therapy and reconstruction via well-known specialists. The paintings positive factors the private remedy protocols of the pinnacle physicians and surgeons focusing on breast affliction. stipulations coated contain benign and malignant tumors, endocrine and stressful issues, and adolescent and grownup difficulties in either men and women. Key positive aspects: - includes authoritative recommendation according to the scientific adventure of famous investigators - offers an exceptional review of breast illness, beginning with breast screening, and advancing to issues resembling silicone autoimmune disorder and breast reconstruction techniques - Takes a well-rounded method of sufferer remedy, with articles on psychosocial difficulties concerning breast melanoma, and the follow-up care of the breast melanoma sufferer - followed through a CD-ROM with the total textual content and illustrations of the e-book, in absolutely searchable PDF documents viewers: scholars and practitioners in surgical procedure, plastic and reconstructive surgical procedure, oncology, and gynecology.
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Additional resources for Advance Therapy of Breast Disease
11. Haber DA, Fearon ER. The promise of cancer genetics. Lancet 1998;351(Suppl2):SIIl-8. 12. Claus EB, Risch N, Thompson WD. Autosomal dominant inheritance of early-onset breast cancer: implications for risk prediction. Cancer 1994;73:643-5 1. 13. Ford D, Easton DF, Stratton M, et al. Genetic heterogeneity and penetrance analysis of the BRCA- 1 and BRCA-2 genes in breast cancer families. Am J Hum Genet 1998;62:676-89. 14. Borresen AL, Andersen TI, Garber J, et al. Screening for germ line TP53 mutations in breast cancer patients.
Still, no test is perfect. In fact, complete sequencing is known to miss large deletions, such as one of the Dutch founder mutations in BRCA- 1. In general, a positive test result does not mean that an individual has a 100% chance of developing cancer, and a negative result does not guarantee that an individual will not develop breast or ovarian cancer. The test tells little about the specific type of cancer that may develop, the precise age at diagnosis, or how a tumor would respond to treatment, though many of these issues are under active investigation.
45. Powles T, Eeles R, Ashley S, et al. Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial. Lancet 1998;352:98-101. 46. Verhoog LC, Brekelmans CTM, Seynaeve C, et al. Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA- 1. Lancet 1998;351:316-21. 47. Narod SA, Risch H, Moslehi R, et al. Oral contraceptives and the risk of hereditary ovarian cancer. N Engl J Med 1998;339:424-8. 48. Ursin G, Henderson BE, Haile RW, et al.
Advance Therapy of Breast Disease by S. Eva Singletary, Geoffrey L. Robb